Objectification of the stratification criteria in children with appendicular peritonitis for the selective hemoperfusion using the hemosorbent «Hemo-proteazsorb»

Peritonitis treatment in children remains one of the most complicated and urgent problem modern surgery intensive care. Particular attention is paid to therapy aimed remove proinflammatory mediators toxic substances. Hemoperfusion (HP) a method based on elimination substances an endogenous or exogenous nature from patient’s blood by extracorporeal perfusion whole through special sorbent. However, date, there are no clear clinical laboratory criteria for initiation, prolongation completion HP procedure. Purpose – objectify stratification with appendicular peritonitis selective using hemosorbent «Hemo-proteazsorb». Materials methods. The retrospective analysis data 60 patients was provided. Discriminant used. Results. Stratification parameters have been developed HF Conclusions. proposed scheme allows stratify It makes possible control results manipulation make decision whether continue complete HP. Considering different capabilities medical institutions, we recommend after validation these institutions. study carried out accordance principles Helsinki Declaration. protocol approved Local Ethics Committee. informed consent parents research obtained. No conflict interest declared authors. Key words: acute appendicitis, peritonitis, children, hemocorrection, hemoperfusion.